Spada, Albert R. La : rechercher sur Z-Library

Cary, Gregory A., La Spada, Albert R.

Année:

2011

Langue:

english

Fichier:

PDF, 1.26 MB

english, 2011

Androgen Receptor Function in Motor Neuron Survival and Degeneration

Journal:

Physical Medicine and Rehabilitation Clinics of North America

Année:

2008

Langue:

english

Fichier:

PDF, 295 KB

english, 2008

Somatic stability of the expanded CAG trinucleotide repeat in X-linked spinal and bulbar muscular atrophy

Roland Spiegel, Albert R. La Spada, Wolfram Kress, Kenneth H. Fischbeck, Werner Schmid

Journal:

Human Mutation

Année:

1996

Langue:

english

Fichier:

PDF, 872 KB

english, 1996

Trinucleotide repeat expansion in neurological disease

Dr. Albert R. La Spada, Henry L. Paulson, Kenneth H. Fischbeck

Journal:

Annals of Neurology

Année:

1994

Langue:

english

Fichier:

PDF, 995 KB

english, 1994

Déjà vu with a twist: transglutaminases in bioenergetics and transcriptional dysfunction in Huntington's disease

Parsa Kazemi-Esfarjani, Albert R. La Spada

Journal:

EMBO Molecular Medicine

Année:

2010

Langue:

english

Fichier:

PDF, 123 KB

english, 2010

Mitochondrial autophagy in neural function, neurodegenerative disease, neuron cell death, and aging

Yakup Batlevi, Albert R. La Spada

Journal:

Neurobiology of Disease

Année:

2011

Langue:

english

Fichier:

PDF, 304 KB

english, 2011

The Purkinje cell degeneration 5J mutation is a single amino acid insertion that destabilizes Nna1 protein

Lisa Chakrabarti, James T. Neal, Michael Miles, Refugio A. Martinez, Annette C. Smith, Bryce L. Sopher, Albert R. La Spada

Journal:

Mammalian Genome

Année:

2006

Langue:

english

Fichier:

PDF, 1.21 MB

english, 2006

Molecular pathogenesis and cellular pathology of spinocerebellar ataxia type 7 neurodegeneration

Gwenn A. Garden, Albert R. La Spada

Journal:

The Cerebellum

Année:

2008

Langue:

english

Fichier:

PDF, 2.15 MB

english, 2008

Inherited Neurodegenerative Disorders Caused by CAG/Polyglutamine Tract Expansions: Symposium Introduction

Albert R. La Spada, Arthur W. Clark

Journal:

Brain Pathology

Année:

1997

Langue:

english

Fichier:

PDF, 279 KB

english, 1997

Trinucleotide Repeat Instability: Genetic Features and Molecular Mechanisms

Albert R. La Spada

Journal:

Brain Pathology

Année:

1997

Langue:

english

Fichier:

PDF, 1.90 MB

english, 1997

Androgen receptor gene mutations in X-linked spinal and bulbar muscular atrophy

Spada, Albert R. La, Wilson, Elizabeth M, Lubahn, Dennis B, Harding, A. E, Fischbeck, Kenneth H

Journal:

Nature

Année:

1991

Fichier:

PDF, 362 KB

1991

Dynamic mutations on the move in Banff

Spada, Albert R La, Richards, Robert I, Wieringa, Bé

Journal:

Nature Genetics

Année:

2004

Langue:

english

Fichier:

PDF, 298 KB

english, 2004

Meiotic stability and genotype – phenotype correlation of the trinucleotide repeat in X–linked spinal and bulbar muscular atrophy

La Spada, Albert R., Roling, Daniel B., Harding, Anita E., Warner, Carolyn L., Spiegel, Roland, Hausmanowa-Petrusewicz, Irena, Yee, Woon-Chee, Fischbeck, Kenneth H.

Journal:

Nature Genetics

Année:

1992

Fichier:

PDF, 444 KB

1992

Getting a handle on Huntington's disease: silencing neurodegeneration

Journal:

Spada, Albert R La, Weydt, Patrick

Année:

2009

Langue:

english

Fichier:

PDF, 91 KB

english, 2009

Targeting toxic proteins for turnover

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 254 KB

english, 2005

Memantine strikes the perfect balance

Journal:

La Spada, Albert R., Taylor, J. Paul

Année:

2009

Langue:

english

Fichier:

PDF, 2.16 MB

english, 2009

Repeat expansion disease: progress and puzzles in disease pathogenesis

Journal:

Nature Reviews Genetics

Année:

2010

Langue:

english

Fichier:

PDF, 484 KB

english, 2010

The zinc-binding domain of Nna1 is required to prevent retinal photoreceptor loss and cerebellar ataxia in Purkinje cell degeneration (pcd) mice

Lisa Chakrabarti, Jeremiah Eng, Refugio A. Martinez, Stephen Jackson, Jing Huang, Daniel E. Possin, Bryce L. Sopher, Albert R. La Spada

Journal:

Vision Research

Année:

2008

Langue:

english

Fichier:

PDF, 1.21 MB

english, 2008

Repeat meeting’s repeat performance: The Second International Conference on Unstable Microsatellites and Human Disease, Chapel Hill, North Carolina, USA, 17–20 April 1999

Albert R La Spada

Journal:

Trends in Genetics

Année:

1999

Langue:

english

Fichier:

PDF, 71 KB

english, 1999

PPARGC1A/PGC-1α, TFEB, and enhanced proteostasis in Huntington disease: Defining regulatory linkages between energy production and protein–organelle quality control

La Spada, Albert R.

Journal:

Autophagy

Année:

2012

Langue:

english

Fichier:

PDF, 682 KB

english, 2012

Neurodegeneration: A Case of Arrested Development?

Albert R. La Spada

Journal:

Cell

Année:

2006

Langue:

english

Fichier:

PDF, 199 KB

english, 2006

A SCA7 CAG/CTG repeat expansion is stable in Drosophila melanogaster despite modulation of genomic context and gene dosage

Stephen M. Jackson, Alex J. Whitworth, Jessica C. Greene, Randell T. Libby, Sandy L. Baccam, Leo J. Pallanck, Albert R. La Spada

Journal:

Gene

Année:

2005

Langue:

english

Fichier:

PDF, 229 KB

english, 2005

Efficient recombination-based methods for bacterial artificial chromosome fusion and mutagenesis

Bryce L. Sopher, Albert R. La Spada

Journal:

Gene

Année:

2006

Langue:

english

Fichier:

PDF, 337 KB

english, 2006

The Power of the Dark Side: Huntington’s Disease Protein and p53 Form a Deadly Alliance

Albert R. La Spada, Richard S. Morrison

Journal:

Nancy M. Bonini, Albert R. La Spada

Année:

2005

Langue:

english

Fichier:

PDF, 74 KB

english, 2005

Silencing Polyglutamine Degeneration with RNAi

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 133 KB

english, 2005

An Antisense CAG Repeat Transcript at JPH3 Locus Mediates Expanded Polyglutamine Protein Toxicity in Huntington's Disease-like 2 Mice

Brian Wilburn, Dobrila D. Rudnicki, Jing Zhao, Tara Murphy Weitz, Yin Cheng, Xiaofeng Gu, Erin Greiner, Chang Sin Park, Nan Wang, Bryce L. Sopher, Albert R. La Spada, Alex Osmand, Russell L. Margolis,

Journal:

Gwenn A. Garden, Albert R. La Spada

Année:

2011

Langue:

english

Fichier:

PDF, 1.88 MB

english, 2011

Intercellular (Mis)communication in Neurodegenerative Disease

Journal:

Taiji Tsunemi, Albert R. La Spada

Année:

2012

Langue:

english

Fichier:

PDF, 875 KB

english, 2012

PGC-1α at the intersection of bioenergetics regulation and neuron function: From Huntington's disease to Parkinson's disease and beyond

Journal:

Progress in Neurobiology

Année:

2012

Langue:

english

Fichier:

PDF, 610 KB

english, 2012

In vivo expansion of trinucleotide repeats yields plasmid and YAC constructs for targeting and transgenesis

Bryce L Sopher, Scott B Myrick, Julie Y Hong, Annette C Smith, Albert R La Spada

Journal:

Gene

Année:

2000

Langue:

english

Fichier:

PDF, 367 KB

english, 2000

Polyglutamine-Expanded Ataxin-7 Antagonizes CRX Function and Induces Cone-Rod Dystrophy in a Mouse Model of SCA7

Albert R. La Spada, Ying-Hui Fu, Bryce L. Sopher, Randell T. Libby, Xuejiao Wang, Lili Y. Li, David D. Einum, Jing Huang, Daniel E. Possin, Annette C. Smith, Refugio A. Martinez, Kari L. Koszdin, Pipe

Journal:

Année:

2001

Langue:

english

Fichier:

PDF, 947 KB

english, 2001

Erratum

Albert R La Spada, Ying-Hui Fu, Bryce L Sopher, Randell T Libby, Xuejiao Wang, Lili Y Li, David D Einum, Jing Huang, Daniel E Possin, Annette C Smith, Refugio A Martinez, Kari L Koszdin, Piper M Treut

Journal:

Albert R La Spada, J.Paul Taylor

Année:

2001

Langue:

english

Fichier:

PDF, 270 KB

english, 2001

Polyglutamines Placed into Context

Journal:

Mel B Feany, Albert R La Spada

Année:

2003

Langue:

english

Fichier:

PDF, 75 KB

english, 2003

Polyglutamines Stop Traffic: Axonal Transport as a Common Target in Neurodegenerative Diseases

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 41 KB

english, 2003

Androgen Receptor YAC Transgenic Mice Recapitulate SBMA Motor Neuronopathy and Implicate VEGF164 in the Motor Neuron Degeneration

Bryce L Sopher, Patrick S Thomas Jr., Michelle A LaFevre-Bernt, Ida E Holm, Scott A Wilke, Carol B Ware, Lee-Way Jin, Randell T Libby, Lisa M Ellerby, Albert R La Spada

Journal:

The American Journal of Human Genetics

Année:

2004

Langue:

english

Fichier:

PDF, 569 KB

english, 2004

Glutamine Repeats and Neurodegenerative Diseases: Molecular Aspects

Albert R. La Spada

Journal:

Année:

2002

Langue:

english

Fichier:

PDF, 35 KB

english, 2002

Finding a sirtuin truth in Huntington's disease

Journal:

Weydt, Patrick, La Spada, Albert R

Année:

2012

Langue:

english

Fichier:

PDF, 217 KB

english, 2012

Targeting protein aggregation in neurodegeneration - lessons from polyglutamine disorders

Journal:

Expert Opinion on Therapeutic Targets

Année:

2006

Langue:

english

Fichier:

PDF, 166 KB

english, 2006

Visceral Neuropathy and Intestinal Pseudo-Obstruction in a Murine Model of a Nuclear Inclusion Disease

Christine M. Clarke, Cara Plata, Bonnie Cole, Karen Tsuchiya, Albert R. La Spada, Raj P. Kapur

Journal:

Gastroenterology

Année:

2007

Langue:

english

Fichier:

PDF, 1.81 MB

english, 2007

Distinct mechanisms of axonal globule formation in mice expressing human wild type α-synuclein or dementia with Lewy bodies-linked P123H ß-synuclein

Akio Sekigawa, Masayo Fujita, Kazunari Sekiyama, Yoshiki Takamatsu, Taku Hatano, Edward Rockenstein, Albert R La Spada, Eliezer Masliah, Makoto Hashimoto

Journal:

Molecular Brain

Année:

2012

Langue:

english

Fichier:

PDF, 1.05 MB

english, 2012

Autophagy activation and enhanced mitophagy characterize the Purkinje cells ofpcdmice prior to neuronal death

Lisa Chakrabarti, Jeremiah Eng, Nishi Ivanov, Gwenn A Garden, Albert R La Spada

Journal:

Molecular Brain

Année:

2009

Langue:

english

Fichier:

PDF, 2.76 MB

english, 2009

S-Nitrosylation of Dynamin-Related Protein 1 Mediates Mutant Huntingtin-Induced Mitochondrial Fragmentation and Neuronal Injury in Huntington's Disease

Haun, Florian, Nakamura, Tomohiro, Shiu, Alicia D., Cho, Dong-Hyung, Tsunemi, Taiji, Holland, Emily A., La Spada, Albert R., Lipton, Stuart A.

Journal:

Antioxidants & Redox Signaling

Année:

2013

Langue:

english

Fichier:

PDF, 1.26 MB

english, 2013

The many faces of autophagy dysfunction in Huntington's disease: from mechanism to therapy

Cortes, Constanza J., La Spada, Albert R.

Journal:

Drug Discovery Today

Année:

2014

Langue:

english

Fichier:

PDF, 700 KB

english, 2014

Peripheral Androgen Receptor Gene Suppression Rescues Disease in Mouse Models of Spinal and Bulbar Muscular Atrophy

Lieberman, Andrew P., Yu, Zhigang, Murray, Sue, Peralta, Raechel, Low, Audrey, Guo, Shuling, Yu, Xing Xian, Cortes, Constanza J., Bennett, C. Frank, Monia, Brett P., La Spada, Albert R., Hung, Gene

Journal:

Cell Reports

Année:

2014

Langue:

english

Fichier:

PDF, 2.57 MB

english, 2014

FUS is not dysregulated by the spinal bulbar muscular atrophy androgen receptor polyglutamine repeat expansion

Fratta, Pietro, Malik, Bilal, Gray, Anna, La Spada, Albert R., Hanna, Michael G., Fisher, Elizabeth M.C., Greensmith, Linda

Journal:

Neurobiology of Aging

Année:

2013

Langue:

english

Fichier:

PDF, 456 KB

english, 2013

The SAGA Histone Deubiquitinase Module Controls Yeast Replicative Lifespan via Sir2 Interaction

McCormick, Mark A., Mason, Amanda G., Guyenet, Stephan J., Dang, Weiwei, Garza, Renee M., Ting, Marc K., Moller, Rick M., Berger, Shelley L., Kaeberlein, Matt, Pillus, Lorraine, La Spada, Albert R., K

Journal:

Cell Reports

Année:

2014

Langue:

english

Fichier:

PDF, 2.26 MB

english, 2014

Something wicked this way comes: huntingtin